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Anti-IP3 receptor Rabbit pAb (100 μl)
| Reactivity: | H & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | IP3 receptor rabbit polyclonal antibody |
Gene Name: | Inositol 1,4,5-trisphosphate receptor type 1 |
Synonyms: | Itpr1, ITPR1, ACV, CLA4, INSP3R1, IP3R, IP3R1, PPP1R94, SCA15, SCA16, SCA29, inositol 1, 5-trisphosphate receptor type 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human IP3 receptor |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Endoplasmic reticulum |
Predicted MW. | 313 kDa |
Observed MW. | 313 kDa |
Uniprot ID: | Q14643 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | SH-SY5Y, U87 |
IHC/IF | Mouse, Rat | 1: 500-1: 1500 | brain, testis |
Background
Inositol 1,4,5-trisphosphate receptor type 1 is a protein that in humans is encoded by the ITPR1 gene. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.
Images
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Western blot analysis of IP3R1 (GB11742) at dilution of 1: 500 |
 | Immunohistochemistry of paraffin embedded mouse brain using IP3R1 (GB11742) at dilution of 1: 600 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using IP3R1 (GB11742) at dilution of 1: 2400 (400x lens) |
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Immunohistochemistry of paraffin embedded rat testis using IP3R1 (GB11742) at dilution of 1: 2400 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
