Reactivity: | H,M |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | ITPKB rabbit polyclonal antibody |
Gene Name: | Inositol-trisphosphate 3-kinase B |
Synonyms: | Inositol 1,4,5-trisphosphate 3-kinase B, IP3 3-kinase B, IP3K B, InsP 3-kinase B, ITPKB |
Immunogen: | Recombinant protein corresponding to Human ITPKB |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 102 kDa |
Observed MW. | 120 kDa |
Uniprot ID: | P27987, P42335 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse | 1: 500-1: 1000 | lung |
Background
ITPKB regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.
Images
Western blot analysis of ITPKB (GB111533) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |