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| Reactivity: | M,R & M,R |
| Applications: | IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Id1 rabbit polyclonal |
Gene Name: | DNA-binding protein inhibitor ID-1 |
Synonyms: | Inhibitor of DNA binding 1, Inhibitor of differentiation 1, Id1, Id, Id-1, Idb1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Id1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 800-1: 1600 | lung, liver, lymph, colon |
IF | Mouse, Rat | 1: 1500-1: 3000 | testis, lung |
Background
ID (inhibitor of DNA binding) proteins contain a helix-loop-helix (HLH) motif and regulate tissue-specific transcription within several cell lineages. They do not bind DNA directly, but inhibit lineage commitment by binding basic helix-loop-helix (bHLH) transcription factors through their HLH motif. ID1 proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID proteins contribute to cell growth, senescence, differentiation, and angiogenesis. Inhibitor of differentiation or DNA binding-1 (ID1) interacts with the trans activation domain of p65 (p65TAD) both in vitro and in vivo.
Images
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Immunohistochemistry analysis of paraffin-embedded mouse lung using Id1 (GB111182) at dilution of 1: 1500 |
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Immunohistochemistry analysis of paraffin-embedded rat lung using Id1 (GB111182) at dilution of 1: 1500 |
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Immunohistochemistry analysis of paraffin-embedded mouse lymph using Id1 (GB111182) at dilution of 1: 1500 |
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Immunohistochemistry analysis of paraffin-embedded rat lymph using Id1 (GB111182) at dilution of 1: 1500 |
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Immunohistochemistry analysis of paraffin-embedded mouse liver using Id1 (GB111182) at dilution of 1: 1500 |
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Immunohistochemistry analysis of paraffin-embedded rat colon using Id1 (GB111182) at dilution of 1: 1500 |
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Immunofluorescent analysis of paraffin-embedded mouse testis using Id1 (GB111182) at dilution of 1: 1500 |
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Immunofluorescent analysis of paraffin-embedded rat lung using Id1 (GB111182) at dilution of 1: 1500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
