Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Ionotropic Glutamate receptor 2 rabbit polyclonal antibody |
Gene Name: | Glutamate receptor 2 |
Synonyms: | GluR-2, AMPA-selective glutamate receptor 2, GluR-B, HBGR2, GluR-K2, Glur2, Glutamate receptor ionotropic, AMPA 2, GluA2, Gria2 |
Immunogen: | Recombinant protein corresponding to Mouse Ionotropic Glutamate receptor 2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membran, Cytoplasm |
Uniprot ID: | P23819, P19491 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 400-1: 2000 | brain |
Background
Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse.
Images
Immunohistochemistry of paraffin embedded mouse brain using GLUR2 (GB111578) at dilution of 1:400 (300x lens) | |
Immunohistochemistry of paraffin embedded rat brain using GLUR2 (GB111578) at dilution of 1:400 (300x lens) | |
Immunofluorescence of paraffin embedded mouse brain using GLUR2 (GB111578) at dilution of 1:1000 (300x lens) | |
Immunofluorescence of paraffin embedded rat brain using GLUR2 (GB111578) at dilution of 1:1000 (300x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |