Anti-KAT1 / HAT1 Rabbit pAb (100 μl)

Anti-KAT1 / HAT1 Rabbit pAb (100 μl)

Brand: ServiceBio
Cat. #: GB11906-100
Availability: In Stock
$259.00
-+
Reactivity: H,M & H,M,R    
Applications: WB & IHC/IF    
Host Species: Rabbit    
Clonality: Polyclonal    
Full Name:

HAT1 rabbit polyclonal antibody

Gene Name:

Histone acetyltransferase type B catalytic subunit

Synonyms:

Cysteine-S-conjugate beta-lyase, Glutamine transaminase K, GTK, Kyat1, Ccbl1, KATI, Glutamine--phenylpyruvate transaminase, Kynurenine aminotransferase 1, Kat, HAT1

Immunogen:

Recombinant protein corresponding to Mouse HAT1

Isotype:

IgG

Purity:

Affinity purification

Subcellular location:

Nucleus

Predicted MW.

48 kDa

Observed MW.

48 kDa

Uniprot ID:

O14929, Q8BY71, Q5M939




Product Usage Information

Applications

Species

Dilution

Positive Sample

WB

Human, Mouse

1: 500-1: 1000

thymus

IHC/IF

Human, Mouse, Rat

1: 500-1: 2000

colon cancer, testis





Background

Histone acetyltransferase 1, also known as HAT1, is an enzyme encoded by the HAT1 gene. The protein is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are, in turn, imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, in particular, of histone H4, plays an important role in replication-dependent chromatin assembly. To be specific, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and, to a lesser degree, histone H2A at lysine 5.




Images

Western blot analysis of hat1 (GB11906) at dilution of 1: 500

Immunohistochemistry of paraffin embedded human colon cancer using hat1 (GB11906) at dilution of 1: 2000 (250x lens)

Immunohistochemistry of paraffin embedded rat testis using hat1 (GB11906) at dilution of 1: 2000 (250x lens)




Storage

Storage Store at -20°C for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


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