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Anti-KAT5 / Tip60 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Tip60 rabbit polyclonal antibody |
Gene Name: | Histone acetyltransferase KAT5 |
Synonyms: | 60 kDa Tat-interactive protein, Tip60, Histone acetyltransferase HTATIP, Kat5, Lysine acetyltransferase 5, Htatip, Tip60 |
Immunogen: | Recombinant protein corresponding to Mouse Tip60 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Uniprot ID: | Q92993, Q8CHK4, Q99MK2 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 3000 | brain, breast cancer, heart, hippocampus, kidney, liver, lung cancer, testis |
Background
Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair.
Images
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Immunohistochemistry of paraffin embedded human breast cancer using TIP60 (GB111065) at dilution of 1:1000 (400x lens) |
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Immunohistochemistry of paraffin embedded human lung cancer using TIP60 (GB111065) at dilution of 1:2000 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse brain using TIP60 (GB111065) at dilution of 1:1000 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse brain using TIP60 (GB111065) at dilution of 1:2000 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse heart using TIP60 (GB111065) at dilution of 1:2000 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat brain using TIP60 (GB111065) at dilution of 1:2000 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat testis using TIP60 (GB111065) at dilution of 1:2000 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse heart using TIP60 (GB111065) at dilution of 1:2000 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse hippocampus using TIP60 (GB111065) at dilution of 1:2000 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse hippocampus using TIP60 (GB111065) at dilution of 1:2000 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse kidney using TIP60 (GB111065) at dilution of 1:2000 (400x lens) |
| Immunofluorescence of paraffin embedded mouse kidney using TIP60 (GB111065) at dilution of 1:2000 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse liver using TIP60 (GB111065) at dilution of 1:2000 (400x lens) |
 | Immunofluorescence of paraffin embedded rat hippocampus using TIP60 (GB111065) at dilution of 1:2000 (400x lens) |
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Immunofluorescence of paraffin embedded rat testis using TIP60 (GB111065) at dilution of 1:2000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
