Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | KHDRBS3 rabbit polyclonal antibody |
Gene Name: | KH domain-containing, RNA-binding, signal transduction-associated protein 3 |
Synonyms: | Etle, etoile, KHDRBS3, RNA binding protein T Star, SALP, Sam68 like mammalian protein 2, SLM 2, SLM2, T STAR, TSTAR |
Immunogen: | Recombinant protein corresponding to Mouse KHDRBS3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | Q9R226 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 1000 | kidney, brain |
Background
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro . Binds optimally to RNA containing 5'-[AU]UAA-3' as a bipartite motif spaced by more than 15 nucleotides (By similarity). Binds poly(A). RNA-binding abilities are down-regulated by tyrosine kinase PTK6 . Involved in splice site selection of vascular endothelial growth factor (By similarity).
Images
Immunohistochemistry analysis of paraffin embedded human kidney using KHDRBS3 (GB114103) at dilution of 1: 500 | |
Immunohistochemistry analysis of paraffin embedded mouse brain using KHDRBS3 (GB114103) at dilution of 1: 500 | |
Immunohistochemistry analysis of paraffin embedded rat brain using KHDRBS3 (GB114103) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |