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Anti-L1CAM Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Neural cell adhesion molecule L1 |
Synonyms: | NCAM-L1, CD171, L1cam, Caml1, CD171 antigen, HSAS, MASA |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse L1CAM |
Uniprot ID: | P11627 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. / Observed MW. | 141 kDa / 141/220 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | brain, cerebellum, spinal cord, hippocampus |
IHC/IF | Mouse, Rat | 1: 500-1: 4000 | brain |
Background
The protein encoded by L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation.
Images
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Western blot analysis of L1CAM (GB111004) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin embedded rat epencephalon using LICAM (GB111004) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin embedded rat brain using LICAM (GB111004) at dilution of 1: 2000 |
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Immunohistochemistry analysis of paraffin embedded mouse brain using LICAM (GB111004) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
