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Anti-LAMP1 Rabbit pAb (100 μl)
| Reactivity: | H & H,M,R |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | LAMP1 rabbit polyclonal |
Gene Name: | Lysosome-associated membrane glycoprotein 1 |
Synonyms: | LAMP-1, Lysosome-associated membrane protein 1, 120 kDa lysosomal membrane glycoprotein, CD107 antigen-like family member A, LGP-120, LGP-A, CD107a, P2B, Lamp1 |
Immunogen: | Recombinant protein corresponding to Mouse LAMP1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Endosome, Lysosome |
Predicted MW. | 44 kDa |
Observed MW. | 44 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | MCF7, HepG2 |
IHC | Human, Mouse, Rat | 1: 500-1: 1000 | cholangiocarcinoma, breast cancer, small intestine |
Background
LAMP1 (also known as CD107a) is a 90-120 kDa heavily glycosylated membrane protein enriched in the lysosomal membrane. LAMP1 functions to provide selectins with carbohydrate ligands. This protein has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells and may also play a role in tumor cell differentiation and metastasis.
Images
| Western blot analysis of LAMP1 (GB112949) at dilution of 1: 1000 Lane 1: MCF7 cell lysate Lane 2: HepG2 cell lysate |
| Immunohistochemistry analysis of paraffin-embedded human cholangiocarcinoma using LAMP1 (GB112949) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded human breast cancer using LAMP1 (GB112949) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded mouse small intestine using LAMP1 (GB112949) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded rat small intestine using LAMP1 (GB112949) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
