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| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Leukemia inhibitory factor |
Synonyms: | LIF, Differentiation-stimulating factor, D factor, CDF, Melanoma-derived LPL inhibitor, DIA |
Immunogen: | Human recombinant LIF protein expressed in 293F cells |
Uniprot ID: | P15018 |
Isotype: | IgG1,κ |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1: 1000-1: 2000 | colon cancer, endometrial cancer, rectum |
Background
LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface.
Images
| Immunohistochemistry of paraffin embedded human colon cancer using LIF (GB121477) at dilution of 1: 1000 (400x lens) |
| Immunohistochemistry of paraffin embedded human endometrial cancer using LIF (GB121477) at dilution of 1: 1000 (400x lens) |
| Immunohistochemistry of paraffin embedded human rectum using LIF (GB121477) at dilution of 1: 1000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
