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| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | LKB1 rabbit polyclonal antibody |
Gene Name: | Serine/threonine-protein kinase STK11 |
Synonyms: | Liver kinase B1 homolog, LKB1, mLKB1, Stk11, Lkb1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse LKB1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Uniprot ID: | Q9WTK7, D4AE59 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 1000-1: 4000 | bone, brain, lung, spleen, testis |
Background
Liver kinase B1 (LKB1), also known as serine/threonine-protein kinase STK11, is a member of the serine/threonine kinase family. LKB1 is a tumor suppressor that helps control cell structure, apoptosis and energy homeostasis through regulation of numerous downstream kinases. Regulates cell polarity by remodeling the actin cytoskeleton, regulates the inhibition of cell growth signaling pathways in response to low energy levels, regulates autophagy in response to nutrient deprivation, and is involved in DNA damage response by differentiating B-cells in the germinal center.
Images
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Immunohistochemistry of paraffin embedded mouse bone using STK11 (GB111236) at dilution of 1:2000 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse brain using STK11 (GB111236) at dilution of 1:2000 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse lung using STK11 (GB111236) at dilution of 1:2000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using STK11 (GB111236) at dilution of 1:2000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat lung using STK11 (GB111236) at dilution of 1:2000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat testis using STK11 (GB111236) at dilution of 1:2000 (400x lens) |
| Immunofluorescence of paraffin embedded mouse brain using STK11 (GB111236) at dilution of 1:1000 (400x lens) |
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Immunofluorescence of paraffin embedded rat spleen using STK11 (GB111236) at dilution of 1:1000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
