Your shopping cart is empty!
Anti-LONP1/Lon Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | LONP1 rabbit polyclonal antibody |
Gene Name: | Lon protease homolog, mitochondrial |
Synonyms: | Lon protease-like protein, LONP, Mitochondrial ATP-dependent protease Lon, Serine protease 15, Lonp1, Prss15 |
Immunogen: | Recombinant protein corresponding to Mouse LONP1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 106 kDa |
Observed MW. | 106 kDa |
Uniprot ID: | P36776, Q8CGK3, Q924S5 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | heart, kidney |
Background
LONP1(Lon protease homolog, mitochondrial) is also named as LONP, LONHS, HLON, LON, PRSS15, PIM1, MGC1498 and belongs to the peptidase S16 family. It seems to play a major role in the elimination of oxidatively modified proteins in the mitochondrial matrix. LONP1, also a nuclearly encoded and mitochondrially located stress-responsive protease, is involved in heme-mediated ALAS-1 turnover. It recognizes specific surface determinants or folds, initiates proteolysis at solvent-accessible sites, and generates unfolded polypeptides that are then progressively degraded.
Images
 |
Western blot analysis of LONP1 (GB111480) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
