Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | LTBR rabbit polyclonal antibody |
Gene Name: | Tumor necrosis factor receptor superfamily member 3 |
Synonyms: | Lymphotoxin-beta receptor, Ltbr, Tnfcr, Tnfrsf3, LT beta R, LTBETAR, Lymphotoxin B receptor, TNFCR |
Immunogen: | Recombinant protein corresponding to Mouse LTBR |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 45 kDa |
Observed MW. | 45-50 kDa |
Uniprot ID: | P36941, P50284 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, liver |
Background
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin alpha and lymphtoxin beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and transformed cells. Activation of the encoded protein can trigger apoptosis.
Images
Western blot analysis of LTBR (GB111459) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |