Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | MANSC1 rabbit polyclonal |
Gene Name: | MANSC domain-containing protein 1 |
Synonyms: | Mansc1, Loss of heterozygosity 12 chromosomal region 3 protein, LOH12CR3 |
Immunogen: | Recombinant protein corresponding to Mouse MANSC1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 45 kDa |
Observed MW. | 62 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 2000 | brain |
Background
MANSC1 is a 414 amino acid single-pass membrane protein. Expressed throughout the body, MANSC1 contains one MANSC domain and is encoded by a gene that is located on chromosome 12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction.
Images
Western blot analysis of MANSC1 (GB112939) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |