Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | MASPIN rabbit polyclonal antibody |
Gene Name: | Serpin B5 |
Synonyms: | Maspin, Peptidase inhibitor 5, PI-5, Serpinb5, Pi5, Spi5, Spi7, mammary serine proteinase inhibitor, Serpin B |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MASPIN |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Predicted MW. | 42 kDa |
Observed MW. | 42 kDa |
Uniprot ID: | P36952, P70124, P70564 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | colon, uterus, skin |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 3000 | appendix, colon, colon cancer, skin |
Background
SERPINB5, also named as PI-5, Maspin and Serpin B5, belongs to the serpin family and Ov-serpin subfamily. It is a tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, SERPINB5 exhibits no serine protease inhibitory activity.
Images
Western blot analysis of Maspin (GB111040) at dilution of 1: 500 |
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Immunohistochemistry of paraffin embedded human colon cancer using Maspin (GB111040) at dilution of 1: 850 (400x lens) | |
Immunohistochemistry of paraffin embedded human colon using Maspin (GB111040) at dilution of 1: 850 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse colon using Maspin (GB111040) at dilution of 1: 850 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse skin using Maspin (GB111040) at dilution of 1: 850 (400x lens) | |
Immunohistochemistry of paraffin embedded rat colon using Maspin (GB111040) at dilution of 1: 850 (400x lens) | |
Immunohistochemistry of paraffin embedded rat skin using Maspin (GB111040) at dilution of 1: 850 (400x lens) | |
Immunofluorescence of paraffin embedded human appendix using Maspin (GB111040) at dilution of 1: 1700 (400x lens) |
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Immunofluorescence of paraffin embedded mouse colon using Maspin (GB111040) at dilution of 1: 1700 (400x lens) |
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Immunofluorescence of paraffin embedded rat colon using Maspin (GB111040) at dilution of 1: 1700 (400x lens) |
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Immunofluorescence of paraffin embedded rat skin using Maspin (GB111040) at dilution of 1: 1700 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |