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| Reactivity: | M |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MCM5 rabbit polyclonal antibody |
Gene Name: | DNA replication licensing factor MCM5 |
Synonyms: | CDC46, Cell division cycle 46, DNA replication licensing factor, MGC5315, P1-CDC46, MCM5 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MCM5 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Uniprot ID: | P49718 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse | 1: 1000-1: 2000 | bone, testis, plancta, spleen |
Background
The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.
Images
| Immunohistochemistry of paraffin embedded mouse spleen using MCM5 (GB113905) at dilution of 1: 2000 (500x lens |
| Immunohistochemistry of paraffin embedded mouse testis using MCM5 (GB113905) at dilution of 1: 1500 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse bone using MCM5 (GB113905) at dilution of 1: 2000 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse placenta using MCM5 (GB113905) at dilution of 1: 2000 (400x lens) |
| Immunofluorescence of paraffin embedded embedded mouse bone using MCM5 (GB113905) at dilution of 1: 1000 (500x lens) |
| Immunofluorescence of paraffin embedded embedded mouse testis using MCM5 (GB113905) at dilution of 1: 1000 (500x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
