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Anti-MCT1/Monocarboxylic acid transporter 1 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Monocarboxylate transporter 1 |
Synonyms: | MCT, MCT 1, MCT1, SLC16A1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MCT1/Monocarboxylic acid transporter 1 |
Uniprot ID: | P53986 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 53 kDa / 45 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | testis |
Background
Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.
Images
| Western blot analysis of MCT1 (GB114978) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
