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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MED6 rabbit polyclonal antibody |
Gene Name: | Mediator of RNA polymerase II transcription subunit 6 |
Synonyms: | ARC33, hMed6, MED6, mediator complex subunit 6, NY REN 28 |
Immunogen: | Recombinant protein corresponding to Mouse MED6 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 28 kDa |
Observed MW. | 35 kDa |
Uniprot ID: | Q921D4 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 300-1: 1000 | lung |
Background
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Images
| Western blot analysis of MED6 (GB114088) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
