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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MEKK2 rabbit polyclonal antibody |
Gene Name: | Mitogen-activated protein kinase kinase kinase 2 |
Synonyms: | Map3k2, MAP3K2, MEKK2, MEKK2B, Mitogen-activated protein kinase kinase kinase 2 |
Immunogen: | Recombinant protein corresponding to Mouse MEKK2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 70 kDa |
Observed MW. | 70 kDa |
Uniprot ID: | Q9Y2U5, Q61083 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | spleen, kidney, stomach |
Background
Mitogen-activated protein kinase kinase kinase 2 is an enzyme encoded by the MAP3K2 gene. The protein is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate IkappaB kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.
Images
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Western blot analysis of MEKK2 (GB11752) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
