Your shopping cart is empty!
Anti-METTL3 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | N6-adenosine-methyltransferase subunit METTL3 |
Synonyms: | IME4, M6A, methyltransferase like 3, METTL3, MT A70, MTA70, Spo8 |
Immunogen: | Recombinant protein corresponding to Human METTL3 |
Uniprot ID: | Q86U44 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Predicted MW. / Observed MW. | 64 kDa / 70 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, testis |
IHC/IF | Mouse, Rat | 1: 300-1: 900 | testis, placenta |
Background
METTL3 is a key S-adenosyl-L-methionine-binding subunit, which is component of a complex multicomponent enzyme that catalyzes the methylation of internal adenosine residues in eukaryotic mRNA, forming N6-methyladenosine. It contains 2 putative nuclear localization signals and 2 consensus methylation motifs. The calculated molecular weight of METTL3 is 64 kDa, but modified METTL3 is about 65-70 kDa.
Images
| Western blot analysis of METTL3 (GB114688) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse testis using METTL3 (GB114688) at dilution of 1: 300 |
| Immunohistochemistry analysis of paraffin embedded rat placenta using METTL3 (GB114688) at dilution of 1: 300 |
| Immunohistochemistry analysis of paraffin embedded rat testis using METTL3 (GB114688) at dilution of 1: 300 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
