Reactivity: | M,R & M |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | MIP-1 alpha/CCL3 rabbit polyclonal |
Gene Name: | C-C motif chemokine 3 |
Synonyms: | Heparin-binding chemotaxis protein, Macrophage inflammatory protein 1-alpha, MIP-1-alpha, L2G25B, SIS-alpha, Small-inducible cytokine A3, TY-5, Mip1a, Scya3, Ccl3, LD78ALPHA, G0S19-1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MIP-1 alpha/CCL3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. / Observed MW. | 10 kDa / 15 kDa |
Uniprot ID: |
Product Usage Information
WB | Mouse, Rat | 1: 300-1: 600 | brain |
IHC/IF | Mouse | 1: 750-1: 1500 | bone, inflammatory model liver |
Background
This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.
Images
Western blot analysis of MIP1a (GB113793) at dilution of 1: 600 | |
Immunohistochemistry analysis of paraffin embedded mouse bone using MIP1a (GB113793) at dilution of 1: 750 | |
Immunohistochemistry analysis of paraffin embedded mouse Inflammatory model induced by lps(6h) liver using MIP1a (GB113793) at dilution of 1: 750 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |