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| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MK-3 rabbit polyclonal antibody |
Gene Name: | MAP kinase-activated protein kinase 3 |
Synonyms: | MAPKAPK3, 3PK, MAPKAP-K3, MAPKAP3, MAPKAPK-3, MK-3, mitogen-activated protein kinase-activated protein kinase 3, MDPT3, MAPKAP kinase 3, Chromosome 3p kinase |
Immunogen: | Recombinant protein corresponding to Mouse MK-3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 43 kDa |
Observed MW. | 43 kDa |
Uniprot ID: | Q3UMW7, Q66H84 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | heart, muscle |
Background
MAP kinase-activated protein kinase 3 is a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses.
Images
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Western blot analysis of MAPAKAPK-3 (GB11694) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
