Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | MMP9 rabbit polyclonal |
Protein full name | Matrix metalloproteinase-9 |
Synonyms: | MMP9, CLG4B, GELB, MANDP2, MMP-9, 92 kDa type IV collagenase, 92 kDa gelatinase, gelatinase B, matrix metallopeptidase 9 |
Immunogen: | Recombinant protein corresponding to Rat MMP9 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human | 1: 200-1: 1000 | kidney, stomach cancer |
IF | Human | 1: 200-1: 500 | kidney, stomach cancer |
Background
May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
Images
Immunohistochemistry analysis of paraffin-embedded human kidney using MMP9 (GB11132-2) at dilution of 1:200 |
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Immunohistochemistry analysis of paraffin-embedded human stomach cancer using MMP9 (GB11132-2) at dilution of 1:200 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |