Reactivity: | H,M,R & H |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | MST1 rabbit polyclonal antibody |
Gene Name: | Serine/threonine-protein kinase 4 |
Synonyms: | Stk4, D3F15S2, DNF15S2, HGFL, MSP, NF15S2, Macrophage stimulating 1, MST1 |
Immunogen: | Recombinant protein corresponding to Mouse MST1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. | 56 kDa |
Observed MW. | 56 kDa |
Uniprot ID: | Q13043, Q9JI11 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 1000-1: 1500 | spleen, liver, lung |
IHC/IF | Human | 1: 400-1: 2000 | colon, gastric cancer, lymph node |
Background
The protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds.
Images
Western blot analysis of MST1 (GB11858) at dilution of 1: 1000 |
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Immunohistochemistry of paraffin embedded human colon using MST1 (GB11858) at dilution of 1: 1000 (400x lens) | |
Immunohistochemistry of paraffin embedded human gastric cancer using MST1 (GB11858) at dilution of 1: 1000 (400x lens) |
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Immunohistochemistry of paraffin embedded human lymph node using MST1 (GB11858) at dilution of 1: 1000 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |