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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MX1 rabbit polyclonal antibody |
Gene Name: | Interferon-induced GTP-binding protein Mx1 |
Synonyms: | Influenza resistance protein, Myxoma resistance protein 1, Myxovirus resistance protein 1, Mx1, Mx, IFI78K |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MX1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 72 kDa |
Observed MW. | 72 kDa |
Uniprot ID: | P20591, P09922, P18588 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 800-1: 1600 | kidney, liver |
Background
The Dynamin family of microtubule-associated proteins function as GTPases that are involved in microtubule bundling and endocytosis. In mice, Mx1 (myxovirus resistance protein 1) is member of the Dynamin family that is involved in the immune response to viral infections. Localized to the cytoplasm, Mx1 is localized to the nucleus where, upon induction by IFN-alpha/IFN-beta, it provides selective resistance to infection by the highly lethal H5N1 influenza virus. In humans, MxA and MxB function in a similar manner to Mx1 and Mx2, conferring resistance to specific target viruses. Mx3 is a rat-specific member of the myxovirus resistance protein family.
Images
| Western blot analysis of Mx1 (GB112553) at dilution of 1: 800 |
| Western blot analysis of Mx1 (GB112553) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
