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Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 Mouse mAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | C-C motif chemokine 3 |
Synonyms: | Ccl3, CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3, C-C motif chemokine ligand 3, Macrophage Inflammatory Protein 1 alpha, Tonsillar lymphocyte LD78 alpha protein, MIP-1-alpha |
Immunogen: | Recombinant protein corresponding to Mouse CCL3 |
Uniprot ID: | P10855 |
Isotype: | IgG1,κ |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 2000 | enteritis, hepatitis, nephritis, pneumonia, small intestine, splenitis |
Background
CCL3 is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes through binding to the receptors CCR1, CCR4 and CCR5. CCL3 has been shown to interact with CCL4, and attracts macrophages, monocytes and neutrophils. CCL3 produces a monophasic fever of rapid onset whose magnitude is equal to or greater than that of fevers produced with either recombinant human tumor necrosis factor or recombinant human interleukin-1.
Images
| Immunohistochemistry of paraffin embedded mouse nephritis using ccl3 (GB12687) at dilution of 1: 500 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse pneumonia using ccl3 (GB12687) at dilution of 1: 2000 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse small intestine using ccl3 (GB12687) at dilution of 1: 2000 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse splenitis using ccl3 (GB12687) at dilution of 1: 2000 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat enteritis using ccl3 (GB12687) at dilution of 1: 500 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat nephritis using ccl3 (GB12687) at dilution of 1: 500 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse hepatitis using ccl3 (GB12687) at dilution of 1: 500 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse nephritis using ccl3 (GB12687) at dilution of 1: 500 (400x lens) |
| Immunofluorescence of paraffin embedded mouse pneumonia using ccl3 (GB12687) at dilution of 1: 500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
