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Anti-Mast cell tryptase Mouse mAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Tryptase alpha/beta-1 |
Synonyms: | MCP7, TPS1, TPS2, TPSAB1, TPSB1, Tryptase 1, tryptase alpha/beta 1, Tryptase beta 1, Tryptase I |
Immunogen: | Recombinant protein corresponding to Human Mast cell tryptase |
Uniprot ID: | Q15661 |
Isotype: | IgG2b,κ |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 500-1: 1000 | uterus, skin, lung, colon |
Background
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence.
Images
| Immunohistochemistry analysis of paraffin embedded rat skin using Mast cell tryptase (GB12110) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human lung using Mast cell tryptase (GB12110) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human colon using Mast cell tryptase (GB12110) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse uterus using Mast cell tryptase (GB12110) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse skin using Mast cell tryptase (GB12110) at dilution of 1: 1000 |
| Immunofluorescence analysis of paraffin embedded mouse uterus using Mast cell tryptase (GB12110) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
