Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | N4BP2L2 rabbit polyclonal |
Gene Name: | NEDD4-binding protein 2-like 2 |
Synonyms: | Phosphonoformate immuno-associated protein 5 homolog, N4bp2l2, Pfaap5, Protein from BCRA2 region |
Immunogen: | Recombinant protein corresponding to Mouse N4BP2L2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 66 kDa |
Observed MW. | 66 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | uterus, lung |
Background
PFAAP5 is a 583 amino acid nuclear protein that potentially is involved in transcriptional regulation. PFAAP5 is phosphorylated on Ser 199 in response to DNA damage, probably by ATM or ATR. Primarily expressed in bone marrow, PFAAP5 is dramatically down-regulated after exposure to arsenic compounds, an event which precedes neutropenia.
Images
Western blot analysis of N4BP2L2 (GB112944) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |