Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | NAK/TBK1 rabbit polyclonal |
Gene Name: | Serine/threonine-protein kinase TBK1 |
Synonyms: | T2K, TANK-binding kinase 1, Tbk1, NF kappa B activating kinase, FLJ11330 |
Immunogen: | Recombinant protein corresponding to Mouse NAK/TBK1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 83 kDa |
Observed MW. | 95 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 2000 | liver |
Background
TBK1, also named as tumor necrosis factor (TNF) receptor-associated factor NF-kB activator (TANK)-binding kinase 1 (TBK1), NF-kB-activating kinase (NAK), T2K, is a multimeric kinase that modulates inflammation and autophagy. It is a ubiquitously expressed serine-threonine kinase belonging to the 'noncanonical IkB kinases' (IKKs) recognized for its critical role in regulating type I IFN production . And TBK1 is an important player in yet another critical cellular function, autophagy. This antibody is specific for TBK1.
Images
Western blot analysis of TBK1 (GB112943) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |