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Anti-NCF1 / p47-phox Rabbit pAb (100 μl)
| Reactivity: | M,R & H,M |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | NCF1 rabbit polyclonal antibody |
Gene Name: | Neutrophil cytosol factor 1 |
Synonyms: | Ncf1, NCF1, NCF1A, NOXO2, SH3PXD1A, p47phox, Neutrophil cytosolic factor 1, |
Immunogen: | Recombinant protein corresponding to Mouse NCF1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Predicted MW. | 45 kDa |
Observed MW. | 47 kDa |
Uniprot ID: | P14598, Q09014, F1M707 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | spleen, lung, thymus |
IHC/IF | Human, Mouse | 1: 250-1: 1000 | colon, lung, pneumonia, splenitis |
Background
Neutrophil cytosol factor 1, also known as p47phox, is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Genetic variability in the NCF1 gene has been found to be related to a higher chance of getting autoimmune diseases such as Sjögren's syndrome, rheumatoid arthritis and lupus erythematosus
Images
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Western blot analysis of P47 phox (GB11724) at dilution of 1: 500 |
| Immunohistochemistry of paraffin embedded human colon using p47phox (GB11724) at dilution of 1: 400 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse lung using p47phox (GB11724) at dilution of 1: 400 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse pneumonia using p47phox (GB11724) at dilution of 1: 400 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse splenitis using p47phox (GB11724) at dilution of 1: 400 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
