Reactivity: | M |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | NETO1 rabbit polyclonal |
Gene Name: | Neuropilin and tolloid-like protein 1 |
Synonyms: | Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1, Neto1, Btcl1 |
Immunogen: | Recombinant protein corresponding to Mouse NETO1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 60 kDa |
Observed MW. | 60 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse | 1: 500-1: 1000 | brain, cortex, hippocampus |
Background
NETO1 is a 533 amino acid protein that contains one LDL-receptor class A domain and two CUB domains and is either membrane-bound or secreted. Expressed as three alternatively spliced isoforms, the first two of which are retina-specific and the third of which is found in both retina and brain tissue, NETO1 is thought to be involved in the development and maintenance of neuronal circuitry, possibly playing a role in proper brain function. Human NETO1 shares 95% amino acid identity with its mouse counterpart, suggesting a conserved role between species. The gene encoding NETO1 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases.
Images
Western blot analysis of NEUROPILINANDTOLLOIDLIKE1 (GB112459) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |