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Anti-NFAT2 Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | NFAT2 rabbit polyclonal |
Gene Name: | Nuclear factor of activated T-cells, cytoplasmic 1 |
Synonyms: | NF-ATc1, NFATc1, Nfat2, NFAT transcription complex cytosolic component, NFATc |
Immunogen: | Recombinant protein corresponding to Mouse NFAT2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 400-1: 1000 | skin, lung |
IF | Mouse, Rat | 1: 250-1: 500 | skin, lung |
Background
The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
Images
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Immunohistochemistry analysis of paraffin-embedded mouse skin using NFAT2 (GB111027) at dilution of 1: 800 |
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Immunohistochemistry analysis of paraffin-embedded rat skin using NFAT2 (GB111027) at dilution of 1: 800 |
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Immunohistochemistry analysis of paraffin-embedded rat lung using NFAT2 (GB111027) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
