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Anti-NFIL3 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | NFIL3 rabbit polyclonal antibody |
Gene Name: | Nuclear factor interleukin-3-regulated protein |
Synonyms: | E4 promoter-binding protein 4, Embryo implantation-related NFIL3/E4BP4-like transcription factor, Nfil3, E4bp4, IL3BP1, Transcriptional activator NF-IL3A |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse NFIL3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 51 kDa |
Observed MW. | 51 kDa |
Uniprot ID: | O08750, Q6IMZ0 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 1000-1: 2000 | liver |
Background
NFIL3, also named as E4BP4 and IL3BP1, belongs to the bZIP family and NFIL3 subfamily. It represses transcription from promoters with activating transcription factor (ATF) sites. NFIL3 activates transcription from the interleukin-3 promoter in T-cells. It competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF). It is a component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock. NFIL3 protects pro-B cells from programmed cell death. It is a key regulator of TH2 responses.
Images
 | Western blot analysis of Nfil3 (GB112557) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
