Your shopping cart is empty!
Anti-NFkB Inducing Kinase NIK Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | NFkB Inducing Kinase NIK rabbit polyclonal antibody |
Gene Name: | Mitogen-activated protein kinase kinase kinase 14 |
Synonyms: | MAP3K14, FTDCR1B, HS, HSNIK, NIK, Mitogen-activated protein kinase, kinase, kinase 14, Map3k14 |
Immunogen: | Recombinant protein corresponding to Mouse MAP3K14 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 104 kDa |
Observed MW. | 104 kDa |
Uniprot ID: | Q99558 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | A549, HeLa, HepG2 |
Background
Mitogen-activated protein kinase kinase kinase 14 also known as NF-kappa-B-inducing kinase (NIK) is an enzyme encoded by the MAP3K14 gene. This protein is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-κB activity. It is a critical kinase of the alternative NF-κB activation pathway. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-κB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.
Images
 |
Western blot analysis of NIK (GB11768) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
