Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | NK-2R rabbit polyclonal antibody |
Gene Name: | Substance-K receptor |
Synonyms: | Tacr2, TACR2, NK2R, NKNAR, SKR, TAC2R, Tachykinin receptor 2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse TACR2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 44 kDa |
Observed MW. | 46 kDa |
Uniprot ID: | P21452, P30549, P16610 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | heart, lung |
Background
Substance-K receptor is a protein encoded by the TACR2 gene. This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P.
Images
Western blot analysis of Tacr2 (GB11760) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |