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Anti-NKIRAS1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R & H,M,R & M |
| Applications: | WB & IHC/IF & ICC/IF & IEM |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | NKIRAS1 rabbit polyclonal antibody |
Gene Name: | NF-kappa-B inhibitor-interacting Ras-like protein 1 |
Synonyms: | I-kappa-B-interacting Ras-like protein 1, Kappa B-Ras protein 1, KappaB-Ras1, Nkiras1, KBRAS1 |
Immunogen: | Recombinant protein corresponding to Mouse NKIRAS1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 22 kDa |
Observed MW. | 22 kDa |
Uniprot ID: | Q9NYS0, Q8CEC5 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 300-1: 800 | lymph gland |
Background
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
Images
 | Western blot analysis of Nkiras1 (GB112500) at dilution of 1: 300 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
