Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | NMDAR1 rabbit polyclonal antibody |
Gene Name: | Glutamate receptor ionotropic, NMDA 1 |
Synonyms: | GRIN1, GluN1, MRD8, NMDA1, NMDAR1, NR1, NMD-R1, glutamate ionotropic receptor NMDA type subunit 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse NMDAR1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cell junction |
Uniprot ID: | P35438 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 100-1: 500 | brain, cerebral infarction, epencephalon |
Background
NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors.
Images
Immunohistochemistry of paraffin embedded mouse brain using NMDAR1 (GB11144) at dilution of 1:100 (400x lens) | |
Immunohistochemistry of paraffin embedded rat brain using NMDAR1 (GB11144) at dilution of 1:100 (400x lens) | |
Immunofluorescence of paraffin embedded mouse cerebral infarction using NMDAR1 (GB11144) at dilution of 1:100 (400x lens) | |
Immunofluorescence of paraffin embedded mouse epencephalon using NMDAR1 (GB11144) at dilution of 1:100 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |