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| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | NRF1 rabbit polyclonal antibody |
Gene Name: | Nuclear respiratory factor 1 |
Synonyms: | NRF1, ALPHA-PAL, nuclear respiratory factor 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse NRF1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 54/68 kDa |
Observed MW. | 68 kDa |
Uniprot ID: | Q9WU00, Q16656 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | HeLa, MCF7, A549 |
Background
Nuclear respiratory factor 1, also known as Nrf1, Nrf-1, NRF1 and NRF-1, encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth.
Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication (By similarity).
Images
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Western blot analysis of NRF1 (GB11351) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
