Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | NSD3 rabbit polyclonal antibody |
Gene Name: | Histone-lysine N-methyltransferase NSD3 |
Synonyms: | Nuclear SET domain-containing protein 3, Wolf-Hirschhorn syndrome candidate 1-like protein 1 homolog, WHSC1-like protein 1, Nsd3, Whsc1l1 |
Immunogen: | Recombinant protein corresponding to Human NSD3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Chromosome, Nucleus |
Uniprot ID: | Q6P2L6 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 600-1: 2800 | brain, heart |
Background
Histone methyltransferase. Preferentially dimethylates 'Lys-4' and 'Lys-27' of histone H3 forming H3K2me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression.
Images
Immunohistochemistry of paraffin embedded rat brain using NSD3 (GB112441) at dilution of 1:1400 (400x lens) | |
Immunohistochemistry of paraffin embedded rat heart using NSD3 (GB112441) at dilution of 1:1400 (400x lens) | |
Immunofluorescence of paraffin embedded mouse brain using NSD3 (GB112441) at dilution of 1:650 (400x lens) | |
Immunofluorescence of paraffin embedded mouse heart using NSD3 (GB112441) at dilution of 1:650 (400x lens) | |
Immunofluorescence of paraffin embedded rat brain using NSD3 (GB112441) at dilution of 1:650 (400x lens) | |
Immunofluorescence of paraffin embedded rat heart using NSD3 (GB112441) at dilution of 1:650 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |