Your shopping cart is empty!
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Nck rabbit polyclonal antibody |
Gene Name: | Cytoplasmic protein NCK1 |
Synonyms: | Nck1, NCK1, NCK, NCKalpha, nck-1, NCK adaptor protein 1 |
Immunogen: | Recombinant protein corresponding to Mouse NCK1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 42 kDa |
Observed MW. | 50 kDa |
Uniprot ID: | P16333, Q99M51 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1:500-1:1000 | heart, testis, spleen |
Background
Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2.
Images
 |
Western blot analysis of NCK-1 (GB11815) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
