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Anti-Neuropilin 1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Neuropilin 1 rabbit polyclonal antibody |
Gene Name: | Neuropilin-1 |
Synonyms: | A5 protein, CD304, Nrp1, Nrp |
Immunogen: | Recombinant protein corresponding to Mouse Neuropilin 1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell Membrane |
Uniprot ID: | P97333, Q9QWJ9 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 1300-1: 2800 | brain, liver cancer |
Background
Neuropilin 1 is a membrane-bound coreceptor to a tyrosine kinase receptor for both vascular endothelial growth factor and semaphorin family members. NRP1 was first identified as a semaphorin (SEMA) receptor, involved in axonal guidance in embryonic development. NRP1 was also shown to act as a receptor for vascular endothelial growth factor (VEGF) and a promoter of angiogenesis through its interaction with VEGF-A165 (and other VEGFs) and the receptor tyrosine kinase (RTK) VEGF-R2.
Images
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Immunohistochemistry of paraffin embedded mouse brain using NRP1 (GB111325) at dilution of 1:1400 (400x lens) |
| Immunohistochemistry of paraffin embedded rat brain using NRP1 (GB111325) at dilution of 1:1400 (400x lens) |
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Immunofluorescence of paraffin embedded human liver cancer using NRP1 (GB111325) at dilution of 1:1300 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
