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Anti-Neurturin Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Neurturin rabbit polyclonal antibody |
Gene Name: | Neurturin |
Synonyms: | Nrtn, Neurturin precursor, prepro-neurturin, NTN |
Immunogen: | Recombinant protein corresponding to Mouse Neurturin |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Uniprot ID: | P97463 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 1600 | brain |
Background
Neurturin and GDNF define a new family of neurotrophic factors. Glial cell line-derived neurotrophic factor (GDNF) plays key roles in the control of vertebrate neuron survival and differentiation. Physiological responses to neurturin (NTN) require the presence of receptor tyrosine kinase RET and a novel glycosylphosphatidylinositol linked receptor NTNRalpha. NTN binds to and forms a complex with GFR-a-2 and the Ret PTK and activates the RET receptor tyrosine kinase pathway.
Images
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Immunohistochemistry of paraffin embedded mouse brain using Neurturin (GB111577) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded mouse brain using Neurturin (GB111577) at dilution of 1:1000 (400x lens) |
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Immunofluorescence of paraffin embedded rat brain using Neurturin (GB111577) at dilution of 1:1000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
