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Anti-Nucleophosmin Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Nucleophosmin rabbit polyclonal antibody |
Gene Name: | Nucleophosmin |
Synonyms: | NPM, Nucleolar phosphoprotein B23, Nucleolar protein NO38, Numatrin, Npm1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Nucleophosmin |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Predicted MW. | 33 kDa |
Observed MW. | 40 kDa |
Uniprot ID: | P06748, Q61937, P13084 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | spleen, testis |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 3000 | breast cancer, colon, colon cancer, hepatocarcinoma, lung cancer, lymph node, ovarian cancer, ovary, spleen, testis |
Background
Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation and regulation of tumor suppressors p53/TP53 and ARF. Stimulates APEX1endonuclease activity on apurinic/apyrimidinic double-stranded DNA but inhibits APEX1 endonuclease activity on AP single-stranded RNA. May exert a control of APEX1 endonuclease activity within nucleoli devoted to repair AP on rDNA and the removal of oxidized rRNA molecules.
Images
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Western blot analysis of Nucleophosmin (GB111043) at dilution of 1: 500 |
 | Immunohistochemistry of paraffin embedded human colon cancer using Nucleophosmin (GB111043) at dilution of 1: 3000 (400x lens) |
 | Immunohistochemistry of paraffin embedded human hepatocarcinoma using Nucleophosmin (GB111043) at dilution of 1: 3000 (400x lens) |
 | Immunohistochemistry of paraffin embedded human lung cancer using Nucleophosmin (GB111043) at dilution of 1: 3000 (400x lens) |
 | Immunohistochemistry of paraffin embedded human ovarian cancer using Nucleophosmin (GB111043) at dilution of 1: 3000 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse colon using Nucleophosmin (GB111043) at dilution of 1: 3000 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse lymph node using Nucleophosmin (GB111043) at dilution of 1: 3000 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse ovary using Nucleophosmin (GB111043) at dilution of 1: 3000 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse spleen using Nucleophosmin (GB111043) at dilution of 1: 3000 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse testis using Nucleophosmin (GB111043) at dilution of 1: 3000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat colon using Nucleophosmin (GB111043) at dilution of 1: 3000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat lymph node using Nucleophosmin (GB111043) at dilution of 1: 3000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat ovary using Nucleophosmin (GB111043) at dilution of 1: 3000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat spleen using Nucleophosmin (GB111043) at dilution of 1: 3000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat testis using Nucleophosmin (GB111043) at dilution of 1: 3000 (400x lens) |
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Immunofluorescence of paraffin embedded human breast cancer using Nucleophosmin (GB111043) at dilution of 1: 1400 (400x lens) |
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Immunofluorescence of paraffin embedded human ovarian cancer using Nucleophosmin (GB111043) at dilution of 1: 1400 (400x lens) |
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Immunofluorescence of paraffin embedded rat spleen using Nucleophosmin (GB111043) at dilution of 1: 1400 (400x lens) |
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Immunofluorescence of paraffin-embedded rat testis using Nucleophosmin (GB111043) at dilution of 1: 1400 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
