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Anti-OGDHL Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | OGDHL rabbit polyclonal |
Gene Name: | 2-oxoglutarate dehydrogenase-like, mitochondrial |
Synonyms: | KIAA1290, OGDC E1 like, OGDHL, Alpha-ketoglutarate dehydrogenase-like, 2-oxoglutarate dehydrogenase complex component E1-like |
Immunogen: | Recombinant protein corresponding to Human OGDHL |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 114 kDa |
Observed MW. | 114 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | kidney, colon, brain |
Background
OGDHL(oxoglutarate dehydrogenase-like) is also named as KGDE1KL, FLJ10851, KIAA1290 and belongs to the alpha-ketoglutarate dehydrogenase family. OGDHL is one of the rate-limiting component of the multienzyme OGDH complex (OGDHC) whose malfunction is associated with neuro-degeneration and it is localized only in the mitochondrial fraction and not in the cytosolic or nuclear fractions. OGDHL negatively regulates cell proliferation by inducing apoptosis in cervical cancer cells. It may thus participate in brain-specific control of 2-oxoglutarate distribution between energy production and synthesis of the neurotransmitter glutamate. It has 3 isoforms(114 kDa, 108 kDa, 91 kDa) produced by alternative splicing.
Images
 | Western blot analysis of OGDHL (GB113240) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
