Reactivity: | H & H,M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | OPA3 rabbit polyclonal antibody |
Gene Name: | Optic atrophy 3 protein |
Synonyms: | OPA3, MGA3, Optic atrophy 3 (Iraqi Jewish 'optic atrophy plus'), Optic atrophy 3 |
Immunogen: | Recombinant protein corresponding to Human OPA3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Mitochondrion |
Predicted MW. | 20 kDa |
Observed MW. | 20 kDa |
Uniprot ID: | Q9H6K4 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 200-1: 400 | HeLa, Jurkat, 293T, A549, K562 |
IHC/IF | Human, Mouse, Rat | 1: 700-1: 1400 | gastric cancer, stomach |
Background
The mouse ortholog of this protein co-purifies with the mitochondrial inner membrane. Mutations in this gene have been shown to result in 3-methylglutaconic aciduria type III and autosomal dominant optic atrophy and cataract. Multiple transcript variants encoding different isoforms have been found for this gene.
Images
Western blot analysis of OPA3 (GB112548) at dilution of 1: 200 | |
Immunofluorescence of paraffin embedded human gastric cancer using OPA3 (GB112548) at dilution of 1: 700 (350x lens) | |
Immunofluorescence of paraffin embedded mouse stomach using OPA3 (GB112548) at dilution of 1: 700 (300x lens) | |
Immunofluorescence of paraffin embedded rat stomach using OPA3 (GB112548) at dilution of 1: 700 (350x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |