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Anti-PCGF3 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Polycomb group RING finger protein 3 |
Synonyms: | DONG1, RNF3A, RNF3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse RNF3 |
Uniprot ID: | Q8BTQ0 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 28 kDa / 28 kDa |
Product Usage Information
WB | Human | 1: 500-1: 800 | 293T, Raji, K562 |
Background
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (PubMed:28596365). Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity (By similarity).
Images
| Western blot analysis of PCGF3 (GB115290) at dilution of 1:500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
