Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | PDE10A rabbit polyclonal antibody |
Gene Name: | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A |
Synonyms: | Pde10a, 5''-cyclic phosphodiesterase 10A, cAMP and cAMP-inhibited cGMP 3'', FLJ11894, Phosphodiesterase 10A, Phosphodiesterase 10A1 |
Immunogen: | Recombinant protein corresponding to Mouse PDE10A |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 89 kDa |
Observed MW. | 75 kDa |
Uniprot ID: | Q8CA95, Q9QYJ6 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | brain, testis |
Background
The PDE10A plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides,eliminate cAMP- and cGMP-mediated intracellular signaling by hydrolyzing the cyclic nucleotide to the corresponding nucleoside 5-prime monophosphate. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate.
Images
Western blot analysis of PDE10A (GB111420) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |