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Anti-Prostaglandin D Synthase (Lipocalin) /PDS Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PDS rabbit polyclonal antibody |
Gene Name: | Prostaglandin-H2 D-isomerase |
Synonyms: | Glutathione-independent PGD synthase, Lipocalin-type prostaglandin-D synthase, Prostaglandin-D2 synthase, L-PGDS, PGD2 synthase, PGDS2, Ptgds, PDS |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PDS |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus, Secreted |
Uniprot ID: | O09114, P22057 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1:1500-1:3000 | brain, spinal cord, testis |
Background
PGDS is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). It is a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation.and also functions as a neuromodulator as well as a trophic factor in the central nervous system. PTGDS has also been implicated in the development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier.
Images
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Immunohistochemistry of paraffin embedded mouse brain using ptgds (GB111297) at dilution of 1:1700 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse testis using ptgds (GB111297) at dilution of 1:1700 (400x lens) |
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Immunohistochemistry of paraffin embedded rat testis using ptgds (GB111297) at dilution of 1:1700 (300x lens) |
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Immunohistochemistry of paraffin embedded rat brain using ptgds (GB111297) at dilution of 1:1700 (400x lens) |
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Immunofluorescence of paraffin embedded mouse brain using ptgds (GB111297) at dilution of 1:1700 (400x lens) |
| Immunofluorescence of paraffin embedded mouse spinal cord using ptgds (GB111297) at dilution of 1:1700 (400x lens) |
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Immunofluorescence of paraffin embedded mouse testis using ptgds (GB111297) at dilution of 1:1700 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
