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Anti-PGRMC2 Rabbit pAb (100 μl)
| Reactivity: | M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Membrane-associated progesterone receptor component 2 |
Synonyms: | DG6, PGRMC2, PMBP |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PGRMC2 |
Uniprot ID: | Q80UU9 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 23 kDa / 18/28 kDa |
Product Usage Information
WB | Mouse | 1: 1000-1: 2000 | adipose tissue, liver |
Background
Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan . May serve as a universal non-classical progesterone receptor in the uterus (Probable). Intracellular heme chaperone required for delivery of labile, or signaling heme, to the nucleus. Plays a role in adipocyte function and systemic glucose homeostasis. In brown fat, which has a high demand for heme, delivery of labile heme in the nucleus regulates the activity of heme-responsive transcriptional repressors such as NR1D1 and BACH1 .
Images
| Western blot analysis of PGRMC2 (GB114778) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
