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Anti-PHAPI2 / APRIL Rabbit pAb (100 μl)
| Reactivity: | H & M,R & M,R |
| Applications: | WB & IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PHAPI2 / APRIL rabbit polyclonal |
Gene Name: | Acidic leucine-rich nuclear phosphoprotein 32 family member B |
Synonyms: | Proliferation-related acidic leucine-rich protein PAL31, Anp32b, Pal31, PAL 31, Ssp29, PHAPI2a |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PHAPI2 / APRIL |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. | 31 kDa |
Observed MW. | 31 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | Jurkat |
IHC | Mouse, Rat | 1: 600-1: 1200 | spleen, heart, kidney |
IF | Mouse, Rat | 1: 300-1: 600 | prostate gland, spleen |
Background
ANP32B is a member of the highly conserved acidic leucine-rich nuclear phosphoprotein 32 (ANP32) family. The ANP32 proteins have been implicated in a broad array of physiological processes, including cell differentiation, apoptotic cell death, and cell proliferation. ANP32B was identified as a novel direct substrate for caspase-3 and acted as a negative regulator for leukemic cell apoptosis. ANP32B controls the expression of the dendritic cell maturation factor CD83 by regulating the transport of its mRNA to the cytoplasm. It also modulates the activity of the transcription factor Kruppel-like factor 5 (KLF5).
Images
| Western blot analysis of APRIL (GB112911) at dilution of 1: 1000 Lane 1: Jurkat cell lysate |
| Immunohistochemistry analysis of paraffin-embedded mouse spleen using APRIL (GB112911) at dilution of 1: 1200 |
| Immunohistochemistry analysis of paraffin-embedded rat spleen using APRIL (GB112911) at dilution of 1: 1200 |
| Immunohistochemistry analysis of paraffin-embedded mouse heart using APRIL (GB112911) at dilution of 1: 1200 |
| Immunohistochemistry analysis of paraffin-embedded rat heart using APRIL (GB112911) at dilution of 1: 1200 |
| Immunohistochemistry analysis of paraffin-embedded rat kidney using APRIL (GB112911) at dilution of 1: 1200 |
| Immunofluorescent analysis of paraformaldehyde-fixed rat prostate gland using APRIL (GB112911) at dilution of 1: 600 |
| Immunofluorescent analysis of paraformaldehyde-fixed rat spleen using APRIL (GB112911) at dilution of 1: 600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
